Key Skills

Job Description

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees. Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so. Does this inspire you and feel like a fit? Then we would love to have you join us! Interested in more than one internship with us? We are posting several projects within our Utrecht Genmab site, each with its own research focus, recruitment team, and selection process. Please take time to explore the available projects and apply to a maximum of two that best match your interests and skills. If you apply to two, include the project titles in order of preference in both motivation letters, with a brief explanation of your interest in each. This helps our teams understand your preferences throughout the separate selection processes! The Role How much can we learn about an antibody by fragmenting it inside a mass spectrometer? And how can different fragmentation techniques help us pinpoint its post-translational modifications? We are looking for a curious and motivated MSc student to join our Mass Spectrometry Characterization group in Utrecht. In this internship, you will explore the capabilities of our Orbitrap Eclipse Tribrid instrument and help develop mass spectrometry methods for detailed antibody characterization. Your project will focus on middle-down and top-down approaches, using fragmentation techniques such as HCD, ETD, EThcD and UVPD to investigate antibodies and their modifications. You will explore how different experimental conditions and fragmentation strategies affect the information we can obtain, including the potential of working under native conditions. This is an exploratory method-development project with room to shape your experimental approach together with your supervisors. Translating the instrument’s capabilities into a reliable method will involve testing ideas, troubleshooting challenges and learning from unexpected results. If you enjoy analytical chemistry and want to deepen your practical understanding of protein mass spectrometry, this project offers an opportunity to do both in an antibody research environment. Responsibilities Review relevant literature and work with your supervisors to develop an experimental plan. Develop and optimize middle-down and top-down mass spectrometry methods using the Orbitrap Eclipse Tribrid. Explore and compare fragmentation techniques to improve antibody characterization and localization of post-translational modifications. Interpret experimental results, troubleshoot challenges and propose next steps. Document your experiments and findings in an electronic laboratory notebook. Discuss your progress and present your findings to the Mass Spectrometry Characterization team. Requirements Currently enrolled in a Master’s degree program at a Dutch university in Analytical Chemistry, Analytical Sciences, Chemistry or a related discipline with a strong analytical focus. Relevant coursework in mass spectrometry and an interest in protein analysis. Previous practical experience with LC-MS or protein mass spectrometry would be an advantage. A curious and systematic approach to experimental work, with an interest in understanding why an experiment does or does not work. Willingness to take initiative and gradually work independently, with guidance from experienced colleagues. Good communication skills in English, both written and spoken. This internship must be a formal, mandatory component of your local degree program required for graduation. You must remain enrolled throughout the internship; we cannot consider graduates or students seeking an extracurricular internship. General Information Duration: A minimum of 8 months to allow sufficient time for experimental development and optimization. Preferred start date: 1 March 2027, aligned with our internship cohort so you can join fellow students for onboarding and shared learning activities. Location: Utrecht, Netherlands. Working arrangement: Full-time, onsite internship. The final project scope will be agreed with your supervisors and tailored to the internship duration, experimental progress, and your degree's criteria. Please submit your CV and a motivation letter describing your interest in the project and any relevant coursework or practical experience in mass spectrometry. Intended Recruitment Timeline Application deadline: 3 December 2026. Shortlisting and initial screening: Week of 7 December 2026. Onsite interviews: Week of 14 December 2026. The proposed gross annual base salary range for this position, in the primary location, based on a full time schedule is: EUR750,00---750,00 The final salary offer will depend on several factors, including your skills, qualifications, and experience. In addition to base salary, this position is eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives. Benefits When you join Genmab, you become a part of a culture that supports your physical, financial, social, and emotional well-being. Our benefits include, but are not limited to: Pension Health insurance and wellness benefits Paid time off Employee support programs Further details on eligibility for compensation and benefits based on the role will be provided during the recruitment process. About Genmab Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines. Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X. Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website Job Applicant Privacy Notice (genmab.com). Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the contract.

Core Responsibilities

Develop and optimize middle-down and top-down mass spectrometry methods on an Orbitrap Eclipse Tribrid, comparing fragmentation techniques to characterize antibodies and locate post-translational modifications. Interpret and document results, troubleshoot experiments, propose next steps, and present findings to the Mass Spectrometry Characterization team.

Requirements

Applicants must be enrolled in a relevant Master’s program at a Dutch university, with a strong analytical focus, relevant mass spectrometry coursework, and an internship that is mandatory for graduation. Protein mass spectrometry or LC-MS experience is advantageous; candidates should be curious, systematic, willing to take initiative, and able to communicate effectively in English.

Benefits

• Pension
• Health Insurance
• Wellness Benefits
• Paid Time Off
• Employee Support Programs