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Automation Scientist (Immunology, BioTech)

MAT Research

Leiden
Full-time
2-5 years experience
On-site

Key Skills

Laboratory Automation
Liquid Handling Systems
Robotics
Immunology
Biotechnology
Assay Development
ELISA
Flow Cytometry
PBMC Isolation
Data Analysis
Python
R
SQL
Mechanical Troubleshooting
Data Integrity
GMP/GLP Compliance

Job Description

MAT ResearchHomepage ← Back to matresearch.com MAT ResearchHomepage Automation Scientist (Immunology, BioTech) On-site Leiden, Zuid-Holland, Netherlands Job Description MAT Research is a pioneering company in the field of pyrogen testing, committed to ushering in a new era of ethical and accurate diagnostics. Since 2016, we have been leading the development of the Monocyte Activation Test (MAT), an animal-free alternative to traditional Rabbit Pyrogen Tests. Our ready-to-use MAT kits offer a robust and highly reliable method for detecting a broad range of pyrogens in parenteral drugs. ISO:9001:2015 certified, we uphold the highest standards of quality in all our products and services. By focusing on in-vitro human-based testing, we aim to drastically increase patient safety while saving hundreds of thousands of animal lives each year. We are steadfast supporters of the European Pharmacopoeia's vision to replace animal-based tests with MAT by 2026. For more details, go to our job page. We are looking for an exceptional Automation Scientist with a strong foundation in Immunology and Biotechnology. This pivotal role is designed for an individual passionate about leveraging automation to elevate the efficiency and quality of both our R&D and manufacturing landscapes. Your Key Responsibilities Will Include Strategic Automation Leadership: Formulate and implement strategies and tactics to enhance automation performance across the board. R&D and Manufacturing Automation: Spearhead automation initiatives within research and development, as well as manufacturing processes, to boost throughput and precision. AutoMATR System Management: From design and integration to maintenance, ensure the AutoMATR systems operate seamlessly and effectively. Documentation and Data Integrity: Uphold meticulous documentation practices and guarantee the accuracy and integrity of automation-generated data. To Fulfill These Responsibilities, You Will Develop and optimize automation assays for MAT Research products, including ELISA. Facilitate the setup and troubleshooting of AutoMATR robotics at client sites. Conduct training sessions for both team members and clients, focusing on laboratory automation techniques. Revise and refine SOPs related to operations and automation. Troubleshoot robotics and instrumentation, ensuring efficient error recovery. Design integrated platforms for comprehensive automation of workflows. Innovate automated methods and data solutions to enhance productivity. Regularly maintain robotic platforms to ensure operational excellence. Contribute to cross-functional meetings with insightful presentations of results. Champion data integrity throughout automated processes. Explore and integrate advanced automation and assay strategies, incorporating AI and machine learning. Analyze and report data, employing computational tools as needed. Remain abreast of the latest trends and technologies in automation. Job requirements Living in the Netherlands near Leiden or able to relocate in the short term. Proven experience with liquid handling systems. A Master’s degree and at least 2 years of post-graduate experience in Robotics, Biochemistry, Biotechnology, Automation, Biophysics, or a related field. Solid educational background in Immunology, Engineering, Automated Sciences, Computer Science, Biology, Chemistry, or a related field, with hands-on experience in assay development and execution. Expert-level skills in data analysis software and modern quality management systems. Proficient in generating, analyzing, and interpreting scientific data from robotic platforms. Skilled in mechanical troubleshooting, particularly with liquid handlers. Experienced in programming (R, Python) and script writing to automate tasks. Familiar with data science tools such as Python, R, SQL/no-SQL databases, AWS, Docker, etc. Innovative with an entrepreneurial attitude, looking beyond what is possible and known. Self-starter with teamwork skills, adept at juggling priorities to nail deadlines. Willing to hit the road for occasional business trips. Fluent in English; proficiency in Dutch, German, or French is a major plus. Prior experience in a GMP/GLP and/or ISO 9001 environment is highly desirable. Hands-on experience in PBMC isolations, cellular assays, and analytical-based assays (ELISA, Flow Cytometry) according to regulatory standards such as ICH is an added advantage. Your Compensation Will Be Competitive base salary (Full-time, 40 hrs/week) Twenty-five vacation days per year and your National Holidays off. or My information Fill out the information below Full name * Email address * Phone number * International Afghanistan Afghanistan CV or resume * Upload your CV or resume file Upload a file or drag and drop here Upload a file or drag and drop hereAccepted files: PDF, DOC, DOCX, JPEG and PNG up to 50MB. Questions Please fill in additional questions What is it about MAT Research and this role that particularly interests you? * This role requires you to work on-site. Are you living in the Netherlands near Leiden, or are you able to relocate in the short term without relocation or Visa support? * Can you share a bit with us about your experience with Automated Sciences and Robotics? (Liquid handling systems) * Please elaborate on your experience working with data analysis software and data science tools. ( Related to: Data from robotic platforms, Python, R, SQL/no-SQL databases, AWS, Docker, etc) * Do you have experience with PBMC isolations, cellular assays, and analytical-based assays (ELISA, Flow Cytometry)? Please share some details with us. * Please give 1–2 concrete examples of how you have used AI in laboratory automation, coding, data analysis, or scientific workflows. What were you trying to achieve, how did you use AI, and how did you validate that the output was correct and reliable? * You are about to consent to the retention of your data by MAT Research. MAT Research will retain your data for a maximum of 2 years and is asking you for consent in consideration of compliance with data protection laws and regulations. Plase check the privacy policy for MATR for more information about the processing of your personal data. You can request removal of your data at any point in time. Choose "Yes" to give your consent. * Yes No All fields marked with * are required. All done! Your application has been successfully submitted! Other jobs You've already applied for this job Thank you for your interest - we've already received your application, so this new submission can't be accepted. Your previous application is on file. If you need assistance or believe this is an error, please email us at [email protected]

Core Responsibilities

Lead automation strategy and develop, integrate, maintain, and troubleshoot robotic systems and automated workflows across R&D and manufacturing. Optimize MAT and ELISA assays, uphold documentation and data integrity, analyze and report results, and train colleagues and clients on automation systems.

Requirements

Requires a master's degree in a relevant field and at least two years of postgraduate experience, with hands-on experience in assay development and liquid-handling systems. Candidates should have strong data analysis and programming skills, mechanical troubleshooting ability, and familiarity with data science tools; experience with PBMC isolation, cellular assays, ELISA, Flow Cytometry, and regulated quality environments is advantageous.

Benefits

  • Twenty-Five Vacation Days
  • National Holidays Off

About MAT Research

Industry: Biotechnology Research

Company size: 2-10 employees

We have developed an improved Monocyte Activation Test (MAT) for pyrogen testing. The MAT serves as the replacement for the Rabbit Pyrogen Test and can be used to test parenteral drugs for endotoxin and non-endotoxin contaminations. Our technology uses cryopreserved pooled PBMC. This has made it possible to develop a MAT with both high sensitivity and robustness, ensuring reliability in the field. Monocyte Activation Test (MAT) The Monocyte Activation Test (MAT) is a pyrogen test. MAT uses human blood cells to test for a fever reaction, mimicking the human immune reaction.The MAT serves as the replacement for the Rabbit Pyrogen Test and can be used to test parenteral drugs for endotoxin and non-endotoxin contaminations. Our technology uses cryopreserved pooled PBMC. This has made it possible to develop a MAT with both high sensitivity and robustness, ensuring reliability in the field. The MAT kit includes all the required consumables to perform the Monocyte Activation Test, making it convenient to perform. In addition to the kit we provide consulting services and technical support in setting up the MAT in your organisation.

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