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Analytical Chemist

SeraNovo B.V.

Leiden
Full-time
2-5 years experience
On-site

Key Skills

UPLC Method Development
HPLC Analysis
Small-Molecule Analysis
Method Verification
Method Validation
Stability Testing
Formulation Testing
Data Interpretation
Troubleshooting
Laboratory Operations
Laboratory Inventory Management
Equipment Coordination
Scientific Documentation
Workflow Improvement
Waters UPLC Systems
Empower

Job Description

Analytical Chemist Full-time | Onsite | Leiden, Netherlands SeraNovo develops oral formulations for small-molecule drugs that are difficult to deliver effectively. Our NanoGlass technology is designed to generate amorphous drug nanoparticles during dissolution, helping address bioavailability challenges. We work with emerging biotechs and global pharmaceutical companies, including AstraZeneca, Boehringer Ingelheim and Johnson & Johnson. We’re looking for an Analytical Chemist to join our small team in Leiden. Your results will help guide formulation decisions across multiple development projects. You’ll also have the opportunity to improve our analytical workflows and how the laboratory operates. Approximately 75% of the role is analytical work and 25% is laboratory operations. You’ll report to SeraNovo’s Analytical Lead. What you’ll do Develop and run UPLC methods for small-molecule drug substances and formulations using Waters systems and Empower. Support method verification and validation, formulation testing and stability studies. Review and interpret results, investigate unexpected findings and document your work clearly. Work closely with analytical and formulation scientists across several projects. Help manage laboratory inventory, shipments, equipment servicing and day-to-day organisation. Identify practical improvements to methods and lab workflows, test them with the team and put effective changes into practice. What you bring A degree in chemistry, analytical chemistry, pharmaceutical sciences or a related field, or equivalent relevant experience. Around two years or more of relevant analytical laboratory experience, ideally in pharmaceutical industry or CDMO work. Hands-on experience analysing small molecules by HPLC or UPLC, including practical method development. Experience with method verification or validation and stability testing. A careful, organised approach to your work and the initiative to solve problems rather than simply pass them on. Experience with Waters UPLC systems, Empower, instrument troubleshooting or laboratory coordination is an advantage. Why join SeraNovo? You’ll see how your analytical work influences formulation development and have room to make the lab work better. This is a hands-on role that includes routine testing and practical laboratory responsibilities. For someone who brings ideas and follows them through, there is meaningful scope to develop methods, improve systems and take greater ownership as we grow.

Core Responsibilities

Develop and run UPLC methods, support verification and validation, conduct formulation and stability testing, and interpret and document analytical results. Collaborate with analytical and formulation scientists while supporting laboratory operations and improving methods and workflows.

Requirements

A degree in chemistry, analytical chemistry, pharmaceutical sciences, or a related field—or equivalent relevant experience—is required, along with around two or more years of relevant analytical laboratory experience. Candidates should have hands-on HPLC or UPLC experience with small molecules, practical method development, and experience with method verification or validation and stability testing.

About SeraNovo B.V.

Industry: Pharmaceutical Manufacturing

Company size: 11-50 employees

SeraNovo is a drug formulation company specializing in oral drug delivery and bioavailability enhancement for poorly soluble and complex compounds. We partner with biotech and pharmaceutical companies to solve one of the most critical challenges in drug development: enabling molecules to achieve sufficient solubility, absorption, and in vivo exposure. As drug candidates become increasingly complex, including beyond Rule of 5 (bRo5) compounds, protein degraders, and peptides, formulation and delivery limitations have become a major bottleneck. SeraNovo addresses these challenges at the source. Our proprietary NanoGlass™ technology generates and stabilizes amorphous drug nanoparticles in situ, improving dissolution and oral absorption while maintaining the stability and scalability required for development. Founded in 2017 and based in Leiden, the Netherlands, SeraNovo has successfully addressed difficult formulation challenges for a diverse, global client base, helping to advance promising medical therapies toward clinical success. Based in Leiden, Netherlands, SeraNovo works with global biotech and pharmaceutical partners to advance drug candidates from molecule to viable therapy. Our goal: to become the go-to formulation company for oral drug delivery and bioavailability challenges and ensure no promising drug fails due to formulation limitations.

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