Key Skills

Job Description

Help us uncover how the infant gut microbiome shapes immune development. Working at the UvA Join Us! Do you want to investigate how the microbiome acquired in early life influences innate immunity and pathogen infection in vulnerable infants? Join an NWO Vidi project that combines advanced gut-on-a-chip technology, organoid models and microbiome approaches. You will work in an interdisciplinary setting to establish novel infant gut models and apply it to investigate microbiota–immune-pathogen interactions, generating knowledge that can support future interventions to improve infant health. We welcome applications from candidates with diverse backgrounds, experiences and perspectives. If you recognise yourself in the role but do not meet every listed preference, we encourage you to apply. A good salary Your salary will be determined on the basis of your experience and seniority, in accordance with the Labour agreement. Your grading and therefore the amounts mentioned are based on full employment of 38 hours per week. 232 vacation hours We also offer parental leave, partner leave and social engagement leave. Through the Employment Conditions Menu Card, there are opportunities for even more vacation hours. Financial arrangements On top of your salary, you receive holiday allowance (8%) and a year-end bonus (8.3%). You build up a good pension with ABP. And in addition, we offer many other allowances and schemes. Career development and room for growth The UvA encourages you to continue to professionalise through training courses and open UvA lectures. Family matters Relocating to the Netherlands with your family? Find out about daycare, schooling, health insurance or employment options and support for your partner or spouse. Including the IDCN-network which provides support for your spouse through various training sessions, social activities, and networking events. All About This Vacancy This is what you will do You will establish an anaerobic gut-microbiome-on-a-chip platform tailored to the human infant gut and investigate how early colonisation by commensal bacteria or pathobionts affects the development and function of the infant gut microbiome, innate immune system and mucosal barrier; design and fabricate mesofluidic gut models using the available research facilities; co-culture organoid-derived intestinal epithelium, immune cells and synthetic microbial communities (SynComs) that reflect infant gut physiology; coordinate and maintain the collaboration between mechanical engineers, microbiologists and translational microbiome researchers at Amsterdam UMC; present research findings at scientific conferences and publish results in peer-reviewed journals. What We Ask Of You You have/are a degree (PhD, or equivalent) in Biomedical Engineering, Cell Biology, Molecular Biology, Pharmacology, Biochemistry, or closely related fields. Candidates in the final stages of obtaining their degree are eligible to apply; an excellent background in bioengineering, biomaterials, hands-on experience of primary cell culture, organoids, or microfluidic systems; experience on or willing to learn anaerobic microbial cultivation and characterization techniques; a problem-solving mindset and a strong motivation; detail-oriented and can perform team-oriented in a multi-disciplinary team as well as independently; fluent in English, both writing and speaking, demonstrated by first-author peer-reviewed publication; experience in academic writing and presentation. This Is What We Offer You We offer a temporary employment contract for 38 hours per week for a period of 12 months. An extension for 2 years subsequently follows if we assess your performance positive. The preferred starting date is as soon as possible. The gross monthly salary, based on 38 hours per week and dependent on relevant experience, is €3.706 to €5.760. This does not include 8% holiday allowance and 8.3% year-end allowance. The UFO profile Researcher 4 is applicable. A favourable tax agreement, the ‘30% ruling’, may apply to non-Dutch applicants. The Collective Labour Agreement of Universities of the Netherlands is applicable. Your place at the UvA You will work in this team The Faculty of Science has a student body of around 8,000, as well as 1,800 members of staff working in education, research or support services. Researchers and students at the Faculty of Science are fascinated by every aspect of how the world works, be it elementary particles, the birth of the universe or the functioning of the brain. The Swammerdam Institute for Life Sciences (SILS) is located at the vibrant Amsterdam Science Park. SILS is one of eight institutes of the University of Amsterdam's Faculty of Science (FNWI). With around 240 employees, SILS carries out internationally high-quality life science research and provides education within various university programs. Research is also carried out in close cooperation with the medical, biotech, chemical, flavor, food & agricultural, and high-tech industries, and revolves around 4 main themes, Cell & Systems biology, Neurosciences, Microbiology and Green Life Sciences. The mission of the Molecular Biology and Microbial Food Safety group is to understand the interaction of microbes and their environment. We focus on microbiomes in the human gut and oral cavity in collaboration with our Amsterdam partners the Amsterdam UMC (location AMC) and ACTA. We study the gut microbiome in the context of Inflammatory Bowl disorders and the development of Depression whereas the oral microbiome is linked to Preventitive Dentistry. Want to know more about our organisation? Read more about working at the University of Amsterdam. About The Faculty Of Science Researchers and students at the Faculty of Science are fascinated by every aspect of how the world works, whether it concerns elementary particles, the birth of the universe, or how the brain functions. The Faculty has a student population of approximately 8,000 students, as well as 1,800 staff members working in education, research, or support services. Important to know Your application & contact If you feel the profile fits you, and you are interested in the job, we look forward to receiving your application. You can apply online via the red button. We accept applications until and including 13 October 2026. If you have any questions or do you require additional information? Please contact: Dr. Jianbo Zhang, [email protected] Applications should include the following information (all files besides your cv should be submitted in one single pdf file): a motivation letter and detailed CV including the months (not just years) when referring to your education and work experience; contact information of referees (not reference letters); a list of publications A knowledge security check can be part of the selection procedure. (for details: national knowledge security guidelines) Acquisition in response to this vacancy is not appreciated. Diversity, Equity & Inclusion As an employer, the UvA maintains an equal opportunities policy. We value diversity and are fully committed to being a place where everyone feels at home. We nurture inquisitive minds and perseverance and allow room for persistent questioning. With us, curiosity and creativity are the prevailing culture. Studies show that women and members of underrepresented groups only apply for jobs if they meet 100% of the qualifications. Do you meet the educational requirements but not yet all of the requested experience? The UvA encourages you to apply anyway.

Core Responsibilities

Establish an anaerobic infant gut microbiome-on-a-chip platform and use it to study how early microbial colonization affects the microbiome, innate immunity, and mucosal barrier. Design and fabricate gut models, co-culture intestinal epithelium with immune cells and microbial communities, coordinate interdisciplinary collaborations, and publish and present research findings.

Requirements

Applicants must have or be nearing completion of a PhD or equivalent in biomedical engineering, cell biology, molecular biology, pharmacology, biochemistry, or a related field, with a strong background in bioengineering or biomaterials. Hands-on experience with primary cell culture, organoids, or microfluidic systems is expected; experience with anaerobic microbial cultivation is desirable or candidates must be willing to learn, alongside strong problem-solving, teamwork, independent working, English communication, academic writing, and presentation skills.

Benefits

• Holiday Allowance
• Year-End Bonus
• Pension
• Vacation Leave
• Parental Leave
• Partner Leave
• Social Engagement Leave
• Training and Professional Development
• Potential 30% Tax Ruling